Chordoma of skull base presenting as nasopharyngeal mass

Sant Prakash Kataria; Ashima Batra; Gajender Singh; Sanjay Kumar; Rajeev Sen

doi:10.4103/0976-3147.116426

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Case Report

4 (

Supp 1

); S95-S97

doi:

10.4103/0976-3147.116426

Chordoma of skull base presenting as nasopharyngeal mass

Sant Prakash Kataria, Ashima Batra, Gajender Singh, Sanjay Kumar, Rajeev Sen

Department of Pathology, Pt B.D. Sharma PGIMS, Rohtak, Haryana, India

Address for correspondence: Dr. Ashima Batra H. No. 901 Ward No. 22, Jhang Colony, Rohtak, Haryana India drashimabatra@gmail.com

Journal of Neurosciences in Rural Practice

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This article was originally published by Thieme Medical and Scientific Publishers Private Ltd. and was migrated to Scientific Scholar after the change of Publisher.

Abstract

ABSTRACT

While the nasopharynx is most commonly regarded by the otolaryngologist as a primary site of neoplastic involvement, it is also an avenue of spread of base?of?the?skull tumors presenting as bulging nasopharyngeal masses. Chordoma is a relatively rare tumor of the skull base and sacrum thought to originate from embryonic remnants of the notochord. Chordomas arising from the skull base/clivus are typically locally aggressive with lytic bone destruction. The optimal treatment may be photon/proton radiotherapy alone or combined with a gross total resection, when feasible. We report a case of intracranial chordoma presenting as nasopharyngeal mass.

Keywords

Chordoma

nasopharyngeal mass

skull base

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Conflict of Interest

None declared

References

Nguyen R. P., Salzman K. L., Stambuk H. E., Ahuja A. T., Harnsberger H. R., . Extraosseous Chordoma of the Nasopharynx. AJNR Am J Neuroradiol. 2009;30:803-7.
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Chugh R, Tawbi H, Lucas D. R., Biermann J. S., Schuetze S. M., Baker L. H., . Chordoma: The nonsarcoma primary bone tumor. Oncologist. 2007;12:1344-50.
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Mirra J. M., Della Rocca C, Nelson S. D., Mertens F, . Chordoma.Pathology and genetics of tumours of soft tissue and bone. Lyon, France: IARC Press; 2002. p. :p. 316-7. In: editors
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Yan Z. Y., Yang B. T., Wang Z. C., Xian J. F., Li M, . Primary chordoma in the nasal cavity and nasopharynx: CT and MR imaging findings. AJNR Am J Neuroradiol. 2010;31:246-50.
[Google Scholar]
Cheng T. B., . Nasopharyngeal Chordoma. Singapore Med J. 1963;3:168-70.
[Google Scholar]
Ferraresi V, Nuzzo C, Zoccali C, Marandino F, Vidiri A, Salducca N, et al . Chordoma: Clinical characteristics, management and prognosis of a case series of 25 patients. BMC Cancer. 2010;10:22.
[Google Scholar]
Baratti D, Gronchi A, Pennacchioli E, Lozza L, Colecchia M, Fiore M, et al . Chordoma: Natural history and results in 28 patients treated at a single institution. Ann Surg Oncol. 2003;10:291-6.
[Google Scholar]
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[Google Scholar]

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[1] Nguyen R. P., Salzman K. L., Stambuk H. E., Ahuja A. T., Harnsberger H. R., . Extraosseous Chordoma of the Nasopharynx. AJNR Am J Neuroradiol. 2009;30:803-7.
[Google Scholar]

[2] Mendenhall W. M., Mendenhall C. M., Lewis S. B., Villaret D. B., Mendenhall N. P., . Skull base chordoma. Head Neck. 2005;27:159-65.
[Google Scholar]

[3] Eisemann M. L., . Sphenooccipital chordoma presenting as a nasopharyngeal mass. Ann Otol Rhinol Laryngol. 1980;89:271-5.
[Google Scholar]

[4] Chugh R, Tawbi H, Lucas D. R., Biermann J. S., Schuetze S. M., Baker L. H., . Chordoma: The nonsarcoma primary bone tumor. Oncologist. 2007;12:1344-50.
[Google Scholar]

[5] Mirra J. M., Della Rocca C, Nelson S. D., Mertens F, . Chordoma.Pathology and genetics of tumours of soft tissue and bone. Lyon, France: IARC Press; 2002. p. :p. 316-7. In: editors
[Google Scholar]

[6] Yan Z. Y., Yang B. T., Wang Z. C., Xian J. F., Li M, . Primary chordoma in the nasal cavity and nasopharynx: CT and MR imaging findings. AJNR Am J Neuroradiol. 2010;31:246-50.
[Google Scholar]

[7] Cheng T. B., . Nasopharyngeal Chordoma. Singapore Med J. 1963;3:168-70.
[Google Scholar]

[8] Ferraresi V, Nuzzo C, Zoccali C, Marandino F, Vidiri A, Salducca N, et al . Chordoma: Clinical characteristics, management and prognosis of a case series of 25 patients. BMC Cancer. 2010;10:22.
[Google Scholar]

[9] Baratti D, Gronchi A, Pennacchioli E, Lozza L, Colecchia M, Fiore M, et al . Chordoma: Natural history and results in 28 patients treated at a single institution. Ann Surg Oncol. 2003;10:291-6.
[Google Scholar]

[10] Fleming G. F., Heimann P. S., Stephens J. K., Simon M. A., Ferguson M. K., Benjamin R. S., et al . Dedifferentiated chordoma. Cancer. 1993;72:714-8.
[Google Scholar]

Chordoma of skull base presenting as nasopharyngeal mass

Abstract

ABSTRACT

Keywords

Chordoma

nasopharyngeal mass

skull base

Conflict of Interest

References

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