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Case Report
doi:
10.4103/0976-3147.105608
Wernicke’s encephalopathy and central pontine myelinolysis in hyperemesis gravidarum
Department of Neurology, Faculty of Medicine, Thammasart University, Thailand
Address for correspondence:
Dr. Panee Sutamnartpong
114/7 Laddarom Village, Ratanathibate Road, Saima, Muang, Nonthaburi
Thailand
pansutam@yahoo.com
Journal of Neurosciences in Rural Practice
Disclaimer:
This article was originally published by Thieme Medical and Scientific Publishers Private Ltd. and was migrated to Scientific Scholar after the change of Publisher; therefore Scientific Scholar has no control over the quality or content of this article.
This article was originally published by Thieme Medical and Scientific Publishers Private Ltd. and was migrated to Scientific Scholar after the change of Publisher; therefore Scientific Scholar has no control over the quality or content of this article.
Abstract
ABSTRACT
A pregnant woman, who had been suffering from hyperemesis gravidarum, presented with alteration of consciousness, ocular nystagmus and ataxia. Magnetic Resonance Imaging of the brain showed typical findings of Wernicke’s encephalopathy and central pontine myelinolysis. The clinical features responded dramatically to thiamine supplementation.
Keywords
Central pontine myelinolysis
hyperemesis gravidarum
Wernicke’s encephalopathy
Conflicts of interest
None declared
REFERENCES
- J Neurol Sci. 2009;284:214-6.Hyperemesis gravidarum induced Wernicke’s encephalopathy: Serial clinical, electrophysiological and MR imaging observations.
- [Google Scholar]
- Lancet Neurol. 2007;6:442-55.Wernicke’s encephalopathy: New clinical settings and recent advances in diagnosis and management.
- [Google Scholar]
- Alcohol Res Health. 2003;27:134-42.The role of thiamine deficiency in alcoholic brain disease.
- [Google Scholar]
- (2nd ed). In: San Diego: Academic Press; 1999. p. p. 491-692.Vitamins.Nutritional Biochemistry.
- [Google Scholar]
- Obstet Gynecol Surv. 2006;61:255-68.Hyperemesis gravidarum complicated by Wernicke encephalopathy: Background, case report, and review of the literature.
- [Google Scholar]
- Eur J Neurol. 2010;17:1408-18.EFNS guidelines for diagnosis, therapy and prevention of Wernicke encephalopathy.
- [Google Scholar]
- Neurol Sci. 2012;33:133-5.Neurological complications in hyperemesis gravidarum.
- [Google Scholar]
- BMJ. 1992;305:517-8.Wernicke’s encephalopathy and central pontine myelinolysis associated with hyperemesis gravidarum.
- [Google Scholar]
- Nat Clin Pract Neurol. 2006;2:54-8. quiz 8Wernicke’s encephalopathy: Beyond alcoholism.
- [Google Scholar]
- Curr Opin Clin Nutr Metab Care. 2011;14:610-7.Thiamine supplementation in the critically ill.
- [Google Scholar]
- Metab Brain Dis. 2010;25:97-106.Central pontine myelinolysis: Historical and mechanistic considerations.
- [Google Scholar]
- Br Med J (Clin Res Ed). 1986;292:684-5.Neurological complications associated with parenteral treatment: Central pontine myelinolysis and Wernicke’s encephalopathy.
- [Google Scholar]
- Neurol Sci. 2004;24:407-10.Central pontine myelinolysis induced by hypophosphatemia following Wernicke’s encephalopathy.
- [Google Scholar]