Translate this page into:
Case Report
doi:
10.4103/0976-3147.105608
Wernicke’s encephalopathy and central pontine myelinolysis in hyperemesis gravidarum
Department of Neurology, Faculty of Medicine, Thammasart University, Thailand
Dr. Panee Sutamnartpong 114/7 Laddarom Village, Ratanathibate Road, Saima, Muang, Nonthaburi Thailand pansutam@yahoo.com
Journal of Neurosciences in Rural Practice
Disclaimer:
This article was originally published by Thieme Medical and Scientific Publishers Private Ltd. and was migrated to Scientific Scholar after the change of Publisher.
This article was originally published by Thieme Medical and Scientific Publishers Private Ltd. and was migrated to Scientific Scholar after the change of Publisher.
Abstract
ABSTRACT
A pregnant woman, who had been suffering from hyperemesis gravidarum, presented with alteration of consciousness, ocular nystagmus and ataxia. Magnetic Resonance Imaging of the brain showed typical findings of Wernicke’s encephalopathy and central pontine myelinolysis. The clinical features responded dramatically to thiamine supplementation.
Keywords
Central pontine myelinolysis
hyperemesis gravidarum
Wernicke’s encephalopathy
Conflicts of interest
None declared
REFERENCES
- Hyperemesis gravidarum induced Wernicke’s encephalopathy: Serial clinical, electrophysiological and MR imaging observations. J Neurol Sci. 2009;284:214-6.
- [Google Scholar]
- Wernicke’s encephalopathy: New clinical settings and recent advances in diagnosis and management. Lancet Neurol. 2007;6:442-55.
- [Google Scholar]
- The role of thiamine deficiency in alcoholic brain disease. Alcohol Res Health. 2003;27:134-42.
- [Google Scholar]
- Vitamins.Nutritional Biochemistry. (2nd ed). San Diego: Academic Press; 1999. p. :p. 491-692. In:
- [Google Scholar]
- Hyperemesis gravidarum complicated by Wernicke encephalopathy: Background, case report, and review of the literature. Obstet Gynecol Surv. 2006;61:255-68.
- [Google Scholar]
- EFNS guidelines for diagnosis, therapy and prevention of Wernicke encephalopathy. Eur J Neurol. 2010;17:1408-18.
- [Google Scholar]
- Wernicke’s encephalopathy and central pontine myelinolysis associated with hyperemesis gravidarum. BMJ. 1992;305:517-8.
- [Google Scholar]
- Wernicke’s encephalopathy: Beyond alcoholism. Nat Clin Pract Neurol. 2006;2:54-8. quiz 8
- [Google Scholar]
- Thiamine supplementation in the critically ill. Curr Opin Clin Nutr Metab Care. 2011;14:610-7.
- [Google Scholar]
- Central pontine myelinolysis: Historical and mechanistic considerations. Metab Brain Dis. 2010;25:97-106.
- [Google Scholar]
- Neurological complications associated with parenteral treatment: Central pontine myelinolysis and Wernicke’s encephalopathy. Br Med J (Clin Res Ed). 1986;292:684-5.
- [Google Scholar]
- Central pontine myelinolysis induced by hypophosphatemia following Wernicke’s encephalopathy. Neurol Sci. 2004;24:407-10.
- [Google Scholar]