Are symptoms of restless legs syndrome generated in the periphery of the nervous system or are they born centrally?

REFERENCES

1. Gupta R, Lahan V, Goel D, . Restlessness in right upper limb as sole presentation of restless legs syndrome. J Neurosci Rural Pract. 2013;4:77-9.

   [Google Scholar]
2. Ekbom K. A., . Restless legs: A clinical study. Acta Med Scand. 1945;158:1-122.

   [Google Scholar]
3. Ekbom K, Ulfberg J, . Restless legs syndrome. J Intern Med. 2009;266:419-31.

   [Google Scholar]
4. Ekbom K. A., . Restless legs in amputees. Acta Med Scand. 1961;169:419-21.

   [Google Scholar]
5. Hening W. A., Allen R. P., Walters A. S., Chokroverty S, . Motor Functions and Dysfunctions of Sleep.Sleep Disorders Medicine. In: editor Philadelphia: Saunders; 2009. p. p. 397-435.

   [Google Scholar]
6. Pereira J. C., Alves R. C., . Restless legs syndrome: Is it a functional peripheral neuropathy? Presented as the poster W. 099 at the WASM/ CSS Congress. Canada: Quebec; 2011.

   [Google Scholar]
7. Pereira J. C., Silva-Neto J. L., Pradella-Hallinan M, . Restless legs syndrome in subjects with knee prosthesis: Evidence that symptoms are generated in the periphery. Clinics (Sao Paulo). 2011;66:1955-9.

   [Google Scholar]
8. Pereira J. C., Pradella-Hallinan M, Lins Pessoa H, . Imbalance between thyroid hormones and the dopaminergic system might be central to the pathophysiology restless legs syndrome: A hypothesis. Clinics (Sao Paulo). 2010;65:548-54.

   [Google Scholar]
9. Pereira J. C., Alves R. C., . The labelled. lines principle of the somatosensory physiology might explain the phantom limb phenomenon. Med Hypotheses. 2011;77:853-6.

   [Google Scholar]